منابع مشابه
Sitosterol feeding: chronic animal and clinical toxicology and tissue analysis.
Sitosterol has previously been shown to block cholesterol absorption in both animals and man. Its clinical effectiveness in reducing hypereholesteremia has been repeatedly demonstrated. For periods exceeding 4 years, large amounts of sitosterol have been given daily for maintaining reduction of serum cholesterol concentration. The possibility of adverse side effects resulting from chronic admin...
متن کاملThe Story of Beta-sitosterol- A Review
Aims: Phytosterols are a subgroup of the steroids, as an important class of bioorganic molecules, widespread in plants, animals, marines as well as fungi and have similarity to cholesterol in structure. These compounds have a long history of consumption as food or pharmaceutical products, and generally recognized as safe without undesirable side effects. Place and Duration of Study: Medicinal p...
متن کاملSluggish sitosterol turnover and hepatic failure to excrete sitosterol into bile cause expansion of body pool of sitosterol in patients with sitosterolemia and xanthomatosis.
Sitosterolemia and xanthomatosis are characterized by the development of tendon and tuberous xanthomas at an early age and premature atherosclerosis despite normal plasma cholesterol concentrations. The reason(s) for the xanthoma formation and premature atherosclerosis are not clearly understood. The accumulation of sitosterol in the tissues of these patients could be due to increased uptake of...
متن کاملβ-Sitosterol Lithospermate from Salvia Columbariae
Salvia columbariae extracts were examined for the presence of salvianolic acids by HPLC-MS and NMR. A new salvianolic acid, β-sitosterol lithospermic acid, was found.
متن کاملDiscrimination between cholesterol and sitosterol for absorption in rats.
The intestinal absorption of cholesterol and sitosterol was compared in rats. The intragastric administration of a single emulsified lipid meal containing either 50 mg of [4-14C]cholesterol or [4-14C]sitosterol resulted in the lymphatic absorption of 18.2% and 0.42% of each sterol, respectively, in 6 hr. This difference was unaltered when the mucosal sterol load was equalized by reducing the ch...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation Research
سال: 1958
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.6.3.373